Cell Decision Making Workshop
A workshop sponsored by The National Science Foundation and Rice University
to be held June (9) 10-11, 2013 in Arlington, VA.
Thursday, June 6, 2013
Workshop website has moved to: http://physicsoflivingsystems.org/cdm/
Wednesday, February 13, 2013
Cells
from across the biological kingdoms are continuously engaged in the process of
decision-making. By “decision-making” we mean taking information from its
surroundings (including neighboring cells), processing this data through complex
signal transduction and genetic circuits, and modulating cellular phenotypes in
response. Decisions implies that other choices are made from competing options
and that once made, these choices have some degree of persistence even as
conditions change.
Much of our progress in understanding the circuitry underlying
decision-making as well as the fitness advantages of underlying strategic logic
implemented therein, has come from bacterial systems. Yet, with the renewed
interest on stem cell-based research for normal tissue and malignant tumors,
there is increasing interest in extending these concepts to eukaryotic and
especially mammalian contexts. This workshop will focus on taking stock of our
current state of knowledge of some well-studied systems, such as the
sporulation pathway of B. subtillus,
the general principles that have emerged from these studies and on how we might
begin to apply these findings to more complex cell types. One outcome of the
workshop will be a research roadmap which will assist the NSF with establishing
funding priorities for this interdisciplinary field.
The workshop itself will
last two full days, June 10-11, 2013 (with an social networking session the evening of June 9th) in Northern Virginia and will feature limited
presentations, mixed with extensive discussions.
Your travel expenses including
meals and lodging in Virginia will be paid for and/or reimbursed.
Please contact workshop coordinator Sara Bradley with any questions or concerns.
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